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valtrex and hiv
Aug 24, 2014

Does valtrex affect the hiv test results. Please end this controversial subject. Because different websites like hivandhepatitis does state it affects. But doctors here say it doesnt?Which one is true?? http://www.hivandhepatitis.com/hiv-aids/hiv-aids-topics/hiv-disease-progression/3123-ias-2011-anti-herpes-drugs-reduce-hiv-viral-load-slow-disease-progression

Response from Dr. Wohl

Older studies in the pre-Highly Active Antiretroviral Therapy era found no benefit of acyclovir in terms of protection from progression of AIDS. The studies you mention, done in Africa, indicate that treating HSV may lower HIV levels, possibly by reducing immune activation and the generation of immune cells that HIV can use to replicate. The herps drugs themselves have little to no activity against HIV.

This is different than saying being on herpes drugs will lead to a profound reduction in HIV levels to render one incapable of producing antibodies against the virus or masking its presence. Even HIV meds used as PEP or PrEP can't do that if they fail to prevent infection.

Herpes drugs will not affect HIV tests designed to diagnose HIV infection.

DW



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