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Window Period HIV Ab/Ag Fourth Generation Test
Oct 1, 2013

Dr. Wohl, How long should one wait to test with a fourth generation test, presumably an Abbott Architect (Quest Diagnostics), to be conclusively negative. Would 6-8 weeks be enough for this test regardless of possible exposure type? Does the three month window period apply to this technology or just third generation tests? Thank you in advance for answering this question.

Response from Dr. Wohl

The advantage of the 4th generation test is it reduces the window period significantly compared to older antibody tests. This is because it looks for antibodies as well as actual virus parts. Within 14 days of infection the 4th generation can detect HIV.

See the link below for more info:

http://www.hivguidelines.org/resource-materials/hiv-qa-fact-sheets/window-period-for-hiv-infection/

DW



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