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Questions about re-infection or super-infection
Apr 26, 2012

I've read that unsafe sex between two positive people can lead to a superinfection. However, if the small amount of virus does enter the body, and a person is taking ART, wouldn't that person's drug regimen act as a prophylaxis and kill and/or inhibit the the new virus in much the same way as a post-exposure prophylaxis would in a negative person? Please explain.

Response from Dr. Young

Hello and thanks for posting.

You're correct that a persons taking ART would theoretically be protected against exposure to a new strain of HIV. This works so long as the new strain was sensitive to the ART (but not if the virus was multidrug resistant).

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