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Positive ELISA, indeterminate Western Blot postpartum
Apr 22, 2012

14 months ago, at 5 weeks pregnant, I had a negative HIV test. I was tested a month ago, and results showed positive ELISA and indeterminate WB. I went back to repeat the test and a rapid HIV test was done while I was there, which was negative. I have been with my husband for 2 1/2 years and he swears he has been faithful. What are the chances I have HIV and it just wasn't showing up on the last test I had?

Response from Mr. Cordova

Hi there:

Indeterminate HIV tests can result from a variety of conditions, including pregnancy, due to the development of nonspecific cross-reacting antibodies. I would suggest you repeat your HIV screening test (rapid test, EIA, ELISA). If negative, you're HIV negative. If positive, repeat your Western Blot. If your test is again indeterminate, I'd suggest getting a qualitative HIV PCR DNA. This type of test does not rely on anti-HIV antibodies and can be helpful in sorting out indeterminate antibody-test results. Good luck.

In health,

Richard



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