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25 rares cases with hiv but no antibody, and WB negative, and normal inmunoglobulina
Feb 22, 2012

http://journals.lww.com/aidsonline/Fulltext/2010/06190/Seronegative_HIV_1_infection__a_review_of_the.2.aspx

Since we can explain 25 Rare cases of hiv ..

none have antibodies, the majority has a negative viral load

please read, I need an explanation.

thank you very much

Response from Dr. Hightow-Weidman

hello there- It is exactly as you wrote, since HIV-1 was first recognized there have been only 25 published case reports of patients with confirmed HIV-1 infection who do not have detectable HIV-1 antibodies. This despite the more than 33.4 million people living with HIV worldwide. Also all of these persons were confirmed as having HIV by finding evidence for HIV-1 infection by plasma HIV-1 RNA (viral load), p24 antigen assays, positive DNA PCR, recovery of virus from culture or all. The majority did not have a negative viral load as you stated but most had very high viral loads, rapid disease progression and significant mortality. Hope this helps

LHW



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