25 rares cases with hiv but no antibody, and WB negative, and normal inmunoglobulina
Feb 22, 2012
Since we can explain 25 Rare cases of hiv ..
none have antibodies, the majority has a negative viral load
please read, I need an explanation.
thank you very much
Response from Dr. Hightow-Weidman
hello there- It is exactly as you wrote, since HIV-1 was first recognized there have been only 25 published case reports of patients with confirmed HIV-1 infection who do not have detectable HIV-1 antibodies. This despite the more than 33.4 million people living with HIV worldwide. Also all of these persons were confirmed as having HIV by finding evidence for HIV-1 infection by plasma HIV-1 RNA (viral load), p24 antigen assays, positive DNA PCR, recovery of virus from culture or all. The majority did not have a negative viral load as you stated but most had very high viral loads, rapid disease progression and significant mortality. Hope this helps
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