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Pregnant / positive elisa but negative western blot (POSITIVE ELISA, NEGATIVE WESTERN BLOT, PREGNANT, 2011)

Sep 2, 2011

My OBGYN advised me that my hiv results came back as a "repeatedly reactive" elisa but "negative" western blot. I am currently 10 weeks pregnant. I tested twice (5/2010 & 10/2010) for hiv while pregnant with my 8 month old and both times the test results were negative. My Dr asked not to worry (hard to do) but to be on the safe side asked me to go get some additional blood work (frozen blood test) done at a lab.

I'm completely anxious, nervous and would appreciate any feedback. Thank you so much in advance!

Response from Dr. Frascino


A repeatedly reactive (positive) ELISA and negative confirmatory Western Blot (WB) is considered a negative HIV test result, because the WB test is the more specific testing assay. Pregnancy can induce the production of nonspecific antibodies, which can confound HIV-antibody test results. You can read more about this in the archives in the chapter devoted to pregnancy issues. See link below for a small sample of what can be found in the archives.

Good luck. Be well. I'm here if you need me, but I doubt you will.

Dr. Bob

Positive ELISA, negative Western Blot and Pregnant! Apr 28, 2009

Actual exposure question enclosed
No seroconversion fears (woohoo!)

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