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A switch from Kaletra/truvada/abacavir to Prezista/Norvir/Truvada
May 20, 2011

I have recently been recomended by my new physician to change from Kaletra/abacavir/truvada to Norvir/Prezista/truvada with a cd4 count of 544 and an undetectable viral load. Is this switch a good one? I have been on the Kaletra/truvada/abacavir regiment for 6 years.

Response from Dr. Frascino

Hi,

There is an old adage that "if it isn't broke, don't fix it," which would argue for staying on your Kaletra/abacavir/Truvada regimen, as your viral load is undetectable and CD4 counts quite good (544). However, personally I would favor the newer regimen, Norvir/Prezista/Truvada, mainly to avoid possible long-term complications associated with abacavir. Also Prezista is often better tolerated than Kaletra. It is generally considered safe to switch from one full suppressive regimen to another fully suppressive regimen. I'd also suggest you talk to your HIV specialist and discuss why he's recommended the switch.

Good luck.

Dr. Bob



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