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Post-nPEP testing, do I need more?

Jan 27, 2011

I'm a big fan of yours. Please help answer my questions, I'll donate to your foundation.

About 80 days ago, I had an condom-break accident with a csw. I was prescribed a course of PEP less than 5 hours later. About 2 days after the exposure, I took the csw to take antibody and PCR tests, both of which came out negative.

Today I took my first ELISA test since that possible exposure. This came out non-reactive. In your assessment, do you think I need to take further tests? I know you usually recommend the post-PEP guideline of testing at 3-month and 6-month mark, but does the fact that the lady tested negative for PCR change your assessment?

Please please give me your comments. Thank you very much.

Response from Dr. Frascino


If I decided someone needed a course of PEP, I would also advise them to follow the post-PEP testing guidelines. If information became available shortly after staring a course of PEP that indicated PEP was not really warranted, I would stop the PEP. Basically, what I'm saying is that if an HIV specialist felt you deserved a full course of PEP, you should follow the post-PEP testing guidelines.

Hope that helps.

Dr. Bob

xanax guy again
Hello Dr. Bob

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