Advertisement
The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol
   
Ask the Experts About

Safe Sex and HIV PreventionSafe Sex and HIV Prevention
          
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  
  • Email Email
  • Glossary Glossary


SANCTITY OF 4th GENERATION TESTS,PLEASE REPLY.DONATION AS PROMISED!!
Dec 23, 2010

Dear Doctor,

I really want to ask that if the person really have to be tested at 3 months mark then what is the sanctity of 4th Generation Tests claiming to be exponentially reducing the window period?Then even today also one is relying on 3rd Generation ANTIBODY Test.Are we saying that the 4th Generation tests are not reliable or they are not sensitive enough?.

People are being adviced differently at different forums and are even cleared and have sexual relations with their partner even if they have taken a single 4th Generation tests at say 5th or 6th week post their exposures or even upto 9th or 10th week considering that the DUO tests are conclusive after 4th week.Now its slightly confusing and disturbing also if a person is going through all the answers being posted in different forums.They really need to take pain of every passing hour till they cross 3 months mark.

As per the answers given by Dr Hansfeild or Dr Sean in Medhelp if a person is getting intimated with his/her partner after taking 4th Generation tests after 4 weeks and before 3 months then they are they putting their partner at risk????? If the seroconversion does takes place?And if not then what is the probability of such persons who are negative after taking 4th Generation tests after 4 weeks but still have a chance of seroconverting after that?Are medhelp- base experts/ doctors really putting persons on risk?? Please do answer..

Regards, AS

Response from Dr. Frascino

Hello AS,

There is no "sanctity" of fourth generation tests or DUO tests. I have no doubt that improvements in HIV testing are increasing the accuracy of diagnostic testing and shortening the window period. However, I base my responses on published scientific guidelines, not on "claims." For instance, I have no way of verifying that "DUO tests are conclusive after the 4th week." Detecting anti-HIV antibodies in the blood depends not only on the sensitivity and specificity of the testing assay, but also on host-immune integrity and response. In other words, no matter how good the test is, different peoples' immune systems may take longer to kick in and start making anti-HIV antibodies. I'm confident that with additional time and experience the guidelines will be revised and the window period will be shortened. But so far that has not happened. Consequently the three-month recommendation remains in effect. I prefer to be overly cautious on this point, because missing a diagnosis can have catastrophic consequences. Finally, it's always worth noting if folks would stop putting themselves at risk for HIV, they wouldn't have to worry about window periods!

Dr. Bob



Previous
PLEASE MR. ITALY I DONT WANNA GET HIV
Next
Inconsistent PEP usage after HIV exposure

  
  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS


 
Advertisement



Q&A TERMS OF USE

This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint

Advertisement