Increased rate of infection
Sep 20, 2010
Dear Dr. Bob,
I understand that the risk of infection is somewhere around 5 per 10000 acts of unprotected vaginal intercourse. (infected woman to uninfected man) However, I do understand that the risk is heavily increased during the time of acute infection. Do you know exactly how significant the increase is?
your friend from Toronto.
Response from Dr. Frascino
Hello Toronto Guy,
You are correct: During acute HIV infection the HIV plasma viral load often skyrockets to extremely high levels. Most of these folks are not on antiretrovirals and many do not even know they are infected. Consequently the HIV-transmission rate is markedly increased. I can't tell you "exactly how significant the increase is" because it depends on many variables, including viral strain and the HIV plasma viral load at the time of exposure.
Hope that helps.
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