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prezista and isentress

Jul 25, 2010

My Dr. recently changed my regimen from kaletra plus truvada to prezista plus isentress. Since thats only 2 arv's versus 3,(not counting norvir), is this strong enough? I have an undetectable viral load (7 years) but t-cells only in the 200 range. I was having side effect problems before the switch which are much improved now. I haven't heard of anyone else on this combo.

Response from Dr. Frascino


Personally I would not recommend a two-drug regimen. Depending on your resistance profile, I would consider adding a nucleoside or non-nucleoside to your regimen. The new(ish) non-nucleoside Intelence would be a good choice. Clinical studies have shown this three-drug regimen to be very effective. I'd suggest you discuss this and other options with your HIV specialist. Consider getting a second opinion if your physician continues to recommend only a two-drug regimen.

Good luck.

Dr. Bob

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