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Low Ratio of CD4 and CD 8...AM I infected
Jun 14, 2010

Hello doctor...my HIV ICMA test came out repeatedly reactive but western blot was negative. also my cd 4 count was 667 and cd 8 count was 819...ratio of cd4/cd8 was 0.80...do you think i have hiv. my viral load is undetectable. Please reply...Thanks!!

Response from Dr. Frascino

Hello,

Do I think you have HIV? No, I do not. Rather, I think you've ordered unnecessary laboratory tests and are now confused and scared by the results.

A repeatedly reactive (positive) ICMA plus a negative confirmatory Western Blot test is considered a negative HIV-screening test! Additional testing was not necessary or indicated. Your subsequent undetectable quantitative HIV PCR RNA viral load merely confirmed what we already knew. You are not HIV infected. There was absolutely no indication to obtain a CD4/CD8 panel, as this is not a diagnostic test for HIV. T cell subsets (CD4s and CD8s) can bounce up and down due to a wide variety of causes; a common cold, for instance.

My advice is to stop worrying and start WOO-HOOing. Also, stop getting unnecessary laboratory tests!

Dr. Bob



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