Consistent Low CD4 Count
Mar 22, 2010
I am now 58 years old. I began meds (Sustiva) three and one half years ago. Just over a year ago, because of dreams, my doctor switched me to Truvada, Reyataz, and Norvir. My CD4 count was under 120 when I started treatment with a high viral load. I am tested every three months. With one exception, my viral load has been undetectable. My CD4 usually wavers between 180 and 230. Though I have not become ill, it is a constant concern. Is there anything I should discuss with my doctor?
Response from Dr. Frascino
Unfortunately, not everyone responds to combination antiretroviral therapy (cART) exactly the same way. You have had an excellent virologic response (viral load plummeting from "high" to undetectable), but a much less impressive immunologic response (CD4 rising only moderately from 120 to 180-230). There are a number of potential reasons for a less than optimal CD4 response to cART. See below. Unfortunately, we do not have a reliable, safe and effective means for treating some of these underlying conditions yet. That is why it's critically important for HIVers to begin treatment before there is severe CD4 depletion. Stay tuned to this site. We'll keep you updated as promising new treatment modalities to address problems like yours become available.
Related post from the archive: Stubborn T-Cells
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