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positive ELISA, reactive IFA, no risk....
Feb 12, 2010

My wife is 14 weeks pregnant and had an HIV screening at 12 weeks that came back positive for the ELISA and reactive for the IFA. She tested negative on the ELISA 13 months ago before our first child was born, I tested negative 1 month ago during a life insurance application, and we have no other risk factors that we can imagine. We are waiting on a PCR test, but are extremely anxious. I have read here and elsewhere that ELISA can be wrong during pregnancy, but what about IFA?

Response from Dr. Frascino

Hi,

If your wife has absolutely no risks for HIV, there is absolutely no way she could be HIV infected. Pregnancy can cause false-positive ELISAs and, somewhat more rarely, IFAs as well. With absolutely no risk exposure, the HIV plasma PCR RNA (or DNA) should be undetectable.

Good luck.

Dr. Bob



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