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PEP Guideline Question
Aug 1, 2009

Dear Dr. Bob,

I finally realized that I am addicted to your site since I have to check your new postings every day.

I remember reading one of your threads that PEP does not (or rarely) cause delayed seroconversion. Therefore, is it true that the current PEP Guideline is not really for the sake of PEP, rather for the severity of exposure?

For example, unprotected culliningus on an unknown status lady (PEP not warranted): no matter PEP was administered or not, 3-month testing is conclusive.

Unprotective receptive anal sex with a virally enhanced dude (PEP warranted): No matter PEP was taken or not, 6-month testing is required.

Your still worried Canucks

Response from Dr. Frascino

Hi Still Worried Canuck,

Yep. The post-PEP testing guidelines are the same as testing guidelines for a significant HIV exposure.

Dr. Bob



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