|HIV PCR RNA Quantitative Test Positive (ANOTHER EXAMPLE WHY PCR TESTS SHOULD NOT BE USED FOR ROUTINE HIV SCREENING, 2009)
Jul 30, 2009
I have a protected intercourse and unprotected Oral Sex durimg the months of May and JUNE, and due to my curiosity, I went to the clinic and did a PCR RNA Test which came Positive this was last week, and yesterday I did a spot test which came negitive, I am very nervous, and today I went to the clinic to perform PCR DNA Test and Western Bolt.
What is the accurecy of the PCR RNA Test, I am panic and really thinking of killing myslef.
| Response from Dr. Frascino
You are thinking of killing yourself because you might be HIV positive. Often I skip over these melodramatic posts, as I think they are highly insensitive to those of us who struggle with the challenges of being "virally enhanced" on a daily basis. I should also point out that if I had jumped off the Golden Gate Bridge when I seroconverted in January 1991 (yes, January 1991!!!), I wouldn't be here today to respond to your histrionic post! That said, I am responding primarily to point out one of the recurring messages I stress in this forum. HIV PCR RNA testing is not recommended for routine HIV screening due to the rate of false positives, other technical considerations and cost. (See below.) Your "positive" HIV RNA PCR is most likely a "false positive!"
The risk of acquiring HIV from oral sex is extremely low. Your negative HIV-antibody test is very encouraging (although not yet definitive because you did not wait the full three months before testing). Your follow-up testing will quickly confirm your HIV status which is most likely negative. So if you haven't committed hari-kari in the interim, I'm confident you'll soon be WOO-HOOing. Write back and let us know the outcome (or where to send the funeral flowers).
False Positive PCR (AN EXAMPLE OF WHY PCR TESTS SHOULD NOT BE USED FOR ROUTINE HIV SCREENING) Oct 21, 2008
Dr Bob Actually the Lab called me that they had reconfirmed the test and its negative.I am feeling really good now. Thanks. I will follow your advise and test only after 3 months
Positive HIV DNA PCR Oct 17, 2008
Dr Bob, I just received my HIV DNA PCR Positive. I cannot believe this. I went to local hiv testing center and had negative oraquick after 3 weeks of exposure. I am on Xannax now. How can a handjob from a stripper give me HIV. I am in deep pain and anxiety. I dont want HIV doc but I got it.
hiv through risky handjob Sep 28, 2008
Hi Doc, I went to a dirty strip club where I got a hand job. What if the previous customer's hiv semen came in contact with my urethra through her hand. There was 5mins between me and previous one. I also dont know whether she had sores on her hand or wounds. Please let me know whether I need testing and can I have sex with my wife until 3 months results. I am also promise to send $50 donation for the great work your doing. Thanks
Response from Dr. Frascino
Your HIV-acquisition risk is extremely remote. However, if you remain worried, get a single HIV test at the three-month mark. In the interim, you could use latex condoms with your wife. I'd also recommend leveling with her. (It's the right thing to do.)
The statistical odds are astronomically in your favor that you did not contract HIV from your "risky handjob." Handjobs, in general, are not considered to be a risk for HIV.
Thank you for your donation to the Robert James Frascino AIDS Foundation (www.concertedeffort.org). In return, I'm sending you my good-luck karma that your definitive three-month HIV test will be negative. I'm quite confident it indeed will be negative.
Response from Dr. Frascino
As I have pointed out innumerable times on this site, PCR testing is not recommended for routine HIV diagnostic screening, due to the rate of false positives, other technical concerns and cost. Your HIV-exposure risk was negligible at best and now you have a positive qualitative HIV DNA PCR, which, in turn, has caused you "deep pain and anxiety" to the point you are freaking out and need to take Xanax. I still strongly doubt you are HIV positive based on what you have told me about your potential HIV exposure risk. Your next step should be to see an HIV specialist. He will be able to run the appropriate diagnostic studies to determine your true HIV serostatus. Write back after you've had that determination.
Response from Dr. Frascino
Excellent news! I'll post your update immediately, as I'm sure your initial post worried some of our chronic worried wells! Like you, they too will be relieved.
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