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Is it wise to take PEP for my exposure?
Jul 18, 2009

Dr Bob I recently had an incident where a condom broke with a sex worker and also had some vaginal secretions come in contact with freshly broken skin. I was given a 30 day dose of Truvada as a PEP. Was this a good move? I have read some scary things online about side effects of PEP and noticed how reluctant most hospitals are to give the dose. Why is that? I just can't figure out why the doctors would not want to give a medicine that could lower risks significantly more often, unless it was a very risky and dangerous medicine for people who do not have HIV. The pharmacy even said "Your doctor gave you this because the benefits outweigh the side effects". Sounds scary.

I have also been on Klonopin for about 5 years now. Am I at risk for liver problems due to the Klonopin and alcohol I ingest? Also, are their any reported long term/permanent side effects from Truvada in people who are HIV negative?

Also want to point out, you and LGBT clinics have changed my worldview. You guys are the most patient, understanding, non-judgmental health officials I know. I can be honest about anything and know there is a true desire to help and debunk all the ignorance I was exposed to growing up in a red state!

God Bless Dr B.

Response from Dr. Frascino

Hello Red Stater,

Infectious fluids (including cervical/vaginal secretions) that come into contact with non-intact skin are considered a risk for HIV transmission. Consequently PEP could have been warranted; however, I would need additional information before being able to make a firm recommendation one way or the other.

PEP (post-exposure prophylaxis) is composed of the same potent antiretroviral medications we use to treat HIV/AIDS. Side effects and drug toxicities can occur with PEP. As with all mediations, the potential benefits of taking a drug need to be weighed against the potential side effects and toxicities.

PEP is not offered to anyone who requests it, because in many cases PEP is not warranted. For instance PEP is only recommended for "significant" HIV exposures and it is not felt to be effective if more than 72 hours has elapsed since the HIV exposure. You can read much more about all aspects of PEP in the archives of this forum, including the potential side effects from Truvada.

Good luck with your post-PEP HIV tests!

Dr. Bob



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Dr. Bob, because you did not answer my question, i dont know what to understand.
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Why does Dr. HHH and you differ in this question?? Its certainly not good for us!!

  
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