CVID / PCR-DNA / P24
May 25, 2009
I have quite severe CVID, and through reading your archives am aware that this could cause a false negative with an ELISA test. As such, I took a DNA-PCR & P24 (the latter as a DUO test with ELISA) test - both negative on two occassions, several months apart.
My question is this - I am unable to find any info on the DNA-PCR's ability to detect CRFs. I live in Europe where there are more genetic variations than in the US.
I know it may depend on the test used, but I'm quite nervous about this and no one at the clinic I attended seems able to help - ie. you deal with a general std Dr unless diagnosed positive.
The result report (for the DNA) reads as follows
HIV-1 ENV proviral DNA (gp41 specific, Group M, A-H, & O) Not detected.
HIV-1 LTR proviral DNA (LTR region, Group M, A-H, & O) Not detected.
HIV-1 gag proviral - Not detected.
HIV-1 pol proviral - Not detected.
My common sense would tell me that there would be a crossover in DNA, but I'm obviously no expert!
Thanks a million!
Response from Dr. Frascino
You are correct: Since CRF are in essence combinations of various subtypes, there is indeed homology (genetic overlap). At this point you've had the most sophisticated testing available and I would advise you believe the results. You are HIV negative.
To avoid this conundrum in the future, just be sure to never put yourself at risk!
Be well. Be safe. Stay well.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Bodybuilders With Hiv
- What Does It Mean To Have Herpes Antibodies?
- What Does A Herpes Rash On The Face Look Like?
- What Can You Do To Make A Person More Comfortable Who Has Shingles?
- What Are The Long And Short Term Problems With Genital Warts?
- What Are The Different Types Of Herpes Zosters Or Shingles?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.