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false HIv result
Mar 11, 2009

Hi, I hope you can answer my question soon as me and my husband are really worried. my husband has not exposed to HIV virus at all, no sex with somebody other than me no needle sharing and he is healthy. in order to apply for immigration we both went for HIV testing (EIA). Mine came out negative, his came out inclusive. they sent out his blood sample for WB screening. WB screening came out indeterminate (gp160 was indeterminate and all other proteins were absent). Our physician asked us to do the viral load test, but the result of this test will come out in 2 weeks and it is really hard for us to wait that long. We thought that maybe meanwhile we are waiting for viral load result we can do the rapid test, so we have done it yesterday and thanks to GOD it was negative. I have read in web that sometimes indeterminate results is because some thing interferes, like vaccination, and we were vaccinated with Measley, Mumps, Rubella, Tetanus vaccines and Tuberculosis Skin test (PPD) was done on US(for immigration requirement) a week before we did the EIA test. Here are my questions: 1-How accurate is rapid test? in comparison with EIA. 2- since we have done the rapid test a week after EIA (2 week after vaccination), can it mean that the vaccination affect or "every thing that had interfered in our first test" was gone by the time we have done rapid test. can we trust on rapid test result? Many thanks,

Response from Dr. Frascino

Hello,

1. Both EIA and rapid tests are extremely accurate.

2. I agree your husband is HIV negative. The exact cause of the indeterminate EIA and WB may never be exactly identified, as there are a number of potential causes. You can read about these in detail in the archives. It's possible the vaccinations may have triggered some cross-reacting antibodies. I'm confident the viral load test will reveal an "undetectable" level confirming your husband's negative HIV status.

Dr. Bob



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