Could Hep A&B Vaccination Cause False Negative HIV Antibody Test?
Nov 26, 2008
Dear Dr. Frascino, I'd like to say I've been through a whole lot of sites and I can say without a doubt that you are the best and most dedicated out there. I've also read most of the posts on this site and am shocked at the volume of e-mails you answer... you are truly a wonderful person.
As a result of reading all of your responses, I'd like to keep this brief as I know you are extremely busy...
Can a hep a&b vaccination administered 3 days after being potentially infected with HIV cause continued false negative antibody tests? Would the logic behind this be the same as in when one is co-infected with hep c? Is the bodies immune system busy producing antibodies for the hep and as a result take longer seroconvert? What course of action do you recommend for testing (PCR DNA, RNA, continued elisa, p24) and how long should one test out to in this situation? Long story short tested negative out to 8 months with all (and I mean every one) of the symptoms and the doctors don't know what is going on and I've been tested for most everything... I'm nearing the end of the rope... help. I could really use a woo-hoo :-)
Thank you and God Bless the good work you are doing... you are keeping us afloat.
Response from Dr. Frascino
Hep A and B vaccinations do not cause false-negative HIV-antibody tests. Period. Next question! (As for the hepatitis C-delayed seroconversion story, see below.)
Start WOO-HOOing. It's long overdue!
I REALLY NEED YOU!!!! (HEPATITIS C AND DELAYED HIV SEROCONVERSION) May 20, 2008
Dr. Bob, I asked you awhile back if HEP C would delay HIV seroconversion.
You said that HEP C would not delay HIV seroconversion! However, Dr. McGovern of the body says that HEP C will delay the HIV window period and that someone who was exposed to both should wait until 6 months to 1 year!!!! Before getting a result!
What's up with that????
Now I know my risk (sharing dollar bill to sniff cocaine) was a low risk incident but what should I do????
I got tested for HEP C at 14 weeks....NEGATIVE!
And HIV at 15 and 17 weeks!!!! NEGATIVE
What should I do???? I think that I am ok and then I hear this stuff!?
Response from Dr. Frascino
No, you don't really need me! What you really need is to pay more attention to what both Dr. McGovern and I have told you on multiple occasions: You are HIV negative. I may need to put a restraining order out on you if you continue to ask your same question over and over again in multiple forums. Come on guy! Give it up! Accept the truly wonderful news you're HIV negative and give other worriers a chance to have their concerns addressed, OK?
This is the last time I'm going to go over this information with you, so pay attention! The Centers for Disease Control has published guidelines for health care workers who sustain a significant occupational exposure to a patient coinfected with HIV and hepatitis C viruses. (This is a far cry from snorting coke through a rolled-up Ben Franklin!) The health care worker guidelines for occupational exposure to coinfected patients suggest HIV-antibody testing at baseline, six weeks and twelve weeks after exposure. There is a caveat, however: If, and I must stress this "if," the health care worker develops acute hepatitis C infection, then and only then (I also stress the "then and only then") would additional HIV-antibody testing be recommend. In this case, and only in this case, are HIV tests out to 12 months recommended. Put another way, if the health care worker does not get ill with acute hepatitis C infection, additional tests would not be recommended!
You have tested hepatitis C negative out to 14 weeks. You do not have acute hepatitis C infection. Hence even if you were a health care worker with documented significant exposure to a coinfected patient, you would not need additional HIV testing. I just can't make it any plainer or clearer than that. Those are the facts, plain and simple. How you choose to live with the incontrovertible evidence that you do not have hepatitis C and that you are conclusively HIV negative is now up to you.
So, I'm signing off on this case permanently. If you require additional reassurance, you can either reread my many (too many) responses to your repetitive and ongoing unwarranted worries or you can seek psychological help. Your problem is not virological; it's psychological!
I'll repost Dr. McGovern's and my responses to you below. We are in absolute agreement!
Can you please tell me if my test results are conclusive???? May 9, 2008
Hello, I emailed you a few weeks ago about sharing a dollar bill to sniff cocaine!( Since I have never touched the stuff!!!!)
Anyway, I got a blood test from my doctor and my test came out negative!!!! This was 14 weeks after sharing the dollar bill.
I also got tested for HIV and that was negative!!!!
So in conclusion, would you say that my negative test results are conclusive? Can I forget all about this?
Response from Dr. McGovern
The risk of HCV transmission through sharing a dollar bill is very low. With this negative blood test, I would suggest that you have had adequate testing.
Remember also that cocaine can lead to heart attacks.
Dr. Bob 3rd time asking......donation coming if you answer! Feb 11, 2008
Dr, Bob I hope you answer this Dr. Bob because I have asked numerous times....
My only fears involving HIV is that I shared a dollar bill to sniff cocaine with a group of people...what would the chances be of getting HIV from this? Has it ever happened? What if there was blood on the dollar bill and I didn't notice? Should I get tested? Not due to fears but scientifically speaking.
My second question is....is it possible to get HIV from deep kissing? I have a moderate case of Gingivitis? I was out drinking alcohol and made out with a girl. What are the chances? I know it happened once right? With that married couple in 1997?
Oh and are 3 month tests conclusive?
Please help and I will send a donation!
Response from Dr. Frascino
1. Theoretical chances of contracting HIV via rolled-up-dollar-bill coke sniffing would be negligible to nonexistent. Has it ever happened? Not to my knowledge. However, please note we haven't run studies on this, as the Investigative Review Board and ethics committee would tend to frown on such a clinical trial. Testing would be primarily to put your residual fears permanently to rest.
2. Kissing is not considered to be a significant risk for HIV transmission, even with a moderate case of gingivitis. Once again, if you're worried, get tested! You'll have an accurate result in less than 20 minutes with a rapid test.
3. Yep, three months is conclusive, unless there are extenuating circumstances.
Thanks for your donation (www.concertedeffort.org).
One final piece of advice: Things don't go better with coke! I recommend strongly you stop.
60 bucks already in the mailbox!!!!.....Last question....is my test conclusive? Apr 13, 2008
Dr. Bob, Hello Dr. Bob! I hope everything is going well with you! I just donated 60 bucks, (I am a college student, and thats the best I can do right now) But I will remember to always donate to your foundation in the future. I put the cash in an envelope and sent it this afternoon. Can you answer my 3 last questions?
Just so you know....I am the guy who shared a dollar bill with some people to sniff cocaine some 12 weeks back. Here are my questions.
1) I got a test today and today was 84 days since I shared the dollar bill to sniff coke. I had an oraquick mouth swab test and it came out negative? Am I ok? Can I finally put this behind me? I tested at 6, 8, 10, and 12 weeks, all negative.
2) Are you sure 12 weeks is conclusive? It's not technically 90 days but its 84 or 85. So am I ok? And can you explain why 12 weeks is ok?
3) Also, is French kissing a risk? My gums bleed sometimes and I french kissed a girl at the bar. Does this warrant testing? That was 9 weeks ago!
Again thank you so much for everything! You truly are a great person and I wish nothing but the best for you!!!!!
Response from Dr. Frascino
1. Yes! Your repeatedly negative HIV tests out to 12 weeks are conclusive and definitive. HIV is not your problem. No way. No how. WOO-HOO!
2. Exactly which part of "No way. No how. WOO-HOO!" are you having difficulty understanding? The published guidelines indicate a negative test at three months is definitive. Twelve weeks equals three months. Consequently you are OK, OK?
3. As the old son goes, "You must remember this, a kiss is just a kiss, as time goes by . . . ." Testing is not warranted. As for your bleeding gums, see your dentist and don't forget to floss!
Thanks for your tax-deductible gift to the Robert James Frascino AIDS Foundation (www.concertedeffort.org).
Be well. Stay well. (Stay away from the nose candy!)
I WANT TO GET MARRIED!!!! DON'T HATE ME! May 11, 2008
Dr. Bob, I am so sorry to bother you again! I forget to ask a question in my last post!
I was hoping you could clear something up for me because I was confused from your response.....so just 1 question please! I want to marry my gf and I need to know this before I can!
I am the guy who asked you about the risk of sharing a dollar bill to sniff cocaine/ and french kissing with gingivitis! (Please answer last question forever!!!!)
Now just to jog your memory....shared dollar bill to sniff cocaine with group of people/ waited 15 weeks...test NEGATIVE!!!!!
Kissing with Gingivits....waited 12 weeks....test NEGATIVE!!!!
Both tests were ORAQUICK!
Do I need to retest at 6 months, or is my 15 week and 12 week tests conclusive???? Sometimes you say 6 months....is this one of those cases?
I want to get married but need to know this! I am sorry for asking again!!!!
Response from Dr. Frascino
Maybe you shouldn't make those "last question forever" type statements. Something tells me you're more of a "hey doc, I just thought of another question" type of guy.
Regarding your latest question, your negative results are definitive and conclusive. No additional testing is warranted.
Congratulations on the upcoming nuptials!
Be well. Stay well.
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