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for the very very very few
Oct 24, 2008

hi me again. please answer this question. i believe it is a tough question. its for the rare people. do it for the one rare person. now lets just say a person cant make hiv antibodies. there are a tiny portion of individual like that. how do they test for hiv without using hiv rna or hiv dna test. what test? or does that person just wait to end up in hospital. oh and the cd 4 count is very hard for a doctor to order. most wont do it. because that varies, and just should'nt be done. hope your doing awesome thanks again.

Response from Dr. Frascino

Hello,

The inability to make antibodies is a very serious medical condition called agammaglobulinemia. Infants with this severe immune deficiency often don't survive, as they have no immune defense against many infectious agents. Hypogammaglobulinemia is a reduced, but not absent, ability to make antibodies. Common variable immunodeficiency is another condition in which the immune system mechanisms for making specific antibodies are impaired or deficient. For conditions such as these, a non-antibody-dependent assay would be recommended. The most reliable would be a qualitative HIV PCR DNA or a quantitative HIV PCR RNA.

Dr. Bob



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