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Dr. Bob, Please help me, I really need your help part2
Sep 26, 2008

Dear Dr. Bob, in my last email you mentioned that my test results are conclusive. Of course its really pleasant and heartwarming to hear it from an excellent HIV specialist like you when I have already self-diagnosed myself with HIV. Even though you said my symptoms werent suggestive of ARS, even thinking about those symptoms stop me from moving on with life if I can still call it a life. I had negative antibody at 3 months node and undetectable HIV PCR RNA at 6 weeks. Dr Bob my doctor at school knows you well as I live an hour away from you. I need you to suggest some tests for me because I am sure I cant wait like this for another three months. Is CD4 blood count, PCR DNA 1 and 2 DNA (qualitative) a good test? I accept the false positive probability because nothing could make me feel any worse but instead a negative could make me feel better. I will take your reply to him. I have to do something. I swear neither, its stress nor I exaggerated any symptoms. My doctor did some tests like mono, Chlamydia and hepatitis. (Unfortunately I didnt have any and its still got to be HIV) Dr. Bob, I still have the headache in front and sometimes on the side and back of my head. I heard headache could be a sign of seroconversion. I can feel a lymph node on the right side of my neck and left side of the back of my head which are swollen. I also have few more questions: 1- is my test 100% accurate or 97-99% ? its sad to be that 1% though. 2-Is it true that PCR RNA test can become undetectable after 6 weeks but PCR DNA will never become undetectable? 3-Would you please tell me why my symptoms are not suggestive for ARS. I swear its not stress. Please give me one more chance for a reply. I promise I wont take your time again even if I get a positive test. Yours,

Response from Dr. Frascino

Hello,

CD4 cell counts and PCR DNA (qualitative) tests are not recommended for HIV diagnostic screening. I strongly advise against obtaining these tests.

My assessment and advice remain exactly the same as in my initial response to you. (See below.) You have overwhelming and irrefutable evidence that you are definitively and conclusively HIV negative. How you choose to live with that reality is up to you. Continuing to perseverate on a disease you could not possibly have is counterproductive. I sincerely hope you bring a copy of your questions and my responses to your doctor (particularly since he knows me well!). I strongly advise you be evaluated for psychosomatic illness. We have seen countless folks exactly like you at the Frascino Medical Group. After thorough evaluation, none of them has turned out to be HIV infected, despite the fact they all were "110% convinced" they were HIV positive when they came in for the evaluation.

Get the psychological help you need, not more HIV tests that you certainly don't need!

Good luck.

Dr. Bob

Dr. Bob, Please help me, I really need your help Sep 13, 2008

Dear Dr. Bob, You are a great person who shines light of hope on people like me. I desperately ask you to save this desperate stupid soul who lives an hour away from you. I have already donated 100$ to your foundation and will promise to do it again. please reply to me. I had vaginal sex with a girl about 3 months ago and the condom broke. I also had a cut on my finger which touched her body fluids. I will never forget that night. I had undetectable HIV-1 PCR RNA quantitative test on week 6 and negative antibody test on weeks 4,8,11, 12.5. My last antibody test was done 86 days after exposure and it was an HIV1/2 rapid blood test. All the tests where done in the Bay Area California. The reason I am posting this to you is that, still I dont really have the peace of mind after all and I am afraid if all I got is a false negative and I am one of those unlucky guys who mess up the statistic. I am really going through a horrible time and I would have never wasted your precious time if I wasnt in this bad condition. I had a series of HIV related symptoms which started about 2.5 weeks after exposure. I couldnt find a good reason for them and my doctor also didnt help me at all as I visited him a couple of times. Basically he said he can tell me what I dont have (he says I dont have HIV after my negative test on week 8) . But he cant tell me what I do have. I desperately need you to tell me what could or might be the source of my symptoms and if it could be still HIV related. Here is what I went through when first symptom started. First I had night sweat for two days. I guess I had fever but I didnt check it. First I thought its a simple cold or mild flu but then HIV came to my mind as I had flu shot vaccine last October or November. Then I had pain in arms and legs, pain in my stomach after eating for two weeks. I also got an ulcer on the top of my mouth about 4 days after the onset of symptoms and took about 4 days to heal. Then I had a mild, on and off pencil like or needle feeling on my skin (leg, arm, face) for another two weeks. It wasnt like it bothered me much but I had it anyways. Then again 1 or two weeks of tiredness in my muscles arms and legs mostly. Then kind of headache started for two weeks. Then short of breath for 1 week or two. I had still mild on and off headache in that interval as well. Then Pain in stomach after eating again and on and off headache again. Little before week 11 my lymph nodes under my neck started to hurt and lasted for more than one week (not swollen). I could still feel a different feeling on my neck on the week after. Right now after three month, I still get a mild headache on and off close to my eyes. Basically my symptoms followed each other and when previous one ended the new one started. I had also negative mono test and negative Chlamydia. During the last three months I never had swollen lymph nodes or skin rash or diarrhea. But I vomited once. My lymph node started to hurt 2.5 months after exposure. I though its a late seroconversion. But my test after 86 days is still negative. I am really sorry for such a long email. But I wanted to give you my exact situation and tell you whatever I went through. Do you think I am infected with this HIV? I used to be healthy and had a good immune system but why my body is responding this way? What could be the source of my symptoms. Please help me. There are times that I cant stop crying because of all I did and all I am going through. This is changing my life in any aspect you can name it. When should I test again? Yours,

Response from Dr. Frascino

Hello,

Your repeatedly negative HIV-antibody tests out to 12.5 weeks and your undetectable HIV-1 PCR RNA at six weeks are definitive and conclusive. HIV is not your problem. No way. No how. (No McCain. No Palin!) No further tests are warranted!

Unfortunately, I cannot diagnose the cause of your symptoms over the Internet. (I don't have access to your medical file or laboratory tests nor do I have the benefit of a complete medical history and physical examination.) However, what I can do with absolute certainty is advise you what is not causing your symptoms: it's not HIV!

Your symptoms, by the way, are not worrisome for or suggestive of HIV acute retroviral syndrome (ARS). They are, however, quite consistent with stress, anxiety and psychosomatic illness. If your doctor cannot find a physical cause for your symptoms, I suggest you consider a psychosomatic cause. Psychosomatic illness produces very real symptoms! Certainly the stress of this HIV scare and your deep-seated fear of being HIV infected could be the cause of your problems. That you state "there are times I can't stop crying . . ." would indicate you are clinically depressed. Counseling could help you confront and conquer your fears, depression and anxiety. I urge you to seek the help of a psychologist. Bring a copy of your post and my response to your first visit and show it to your therapist. It will help focus your treatment and speed your recovery.

Thank you for your generous donations to the Robert James Frascino AIDS Foundation (www.concertedeffort.org). They are warmly appreciated.

Good luck.

Dr. Bob



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