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indeterminate test result
Jul 18, 2008

Hello Dr. Please help me with my ambiguous test result. I haven't been able to do anything after i got my results. please help..............

elisa-positive wb-indeterminate RNA-negative

am i HIV+?

Response from Dr. Frascino

Hello,

It's unfortunate that so many people are getting HIV tests, but don't have the expertise to interpret the results! Your HIV screening consisting of a repeatedly reactive ELISA (ELISA positive) and indeterminate Western Blot would be considered an "indeterminate HIV test." There are many potential causes of indeterminate HIV tests. You can read about these in great detail in the archives of this forum. Often a single repeat HIV-screening test (ELISA followed by WB, if the former is positive) taken a few weeks after the initial indeterminate test will clarify the result one way or the other. If the repeat screening tests remains indeterminate, I would recommend a qualitative HIV PCR DNA test. Although not FDA approved for HIV screening, this test can be helpful in sorting out unclear HIV-antibody test results.

HIV RNA testing is not recommended for routine HIV screening, due to the number of false-positive results, other technical concerns and cost. That your HIV RNA was undetectable, however, would be encouraging. You can read more about HIV diagnostic tests in the archives and also in the chapter "HIV Diagnostic Tests" that can be easily accessed on The Body's homepage under the heading "Quick Links."

Good luck.

Dr. Bob



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