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INDETERMINATE RESULTS
May 3, 2008

Hi My first lab report like that see below information. Date (March 08 2008) HIV EIA AB SCREEN -----REPEATEDLY REACTIVE(NON REACTIVE) SEE HIV 1 WESTERN BLOT RESULUT. HIV 1 AB CONFIRMATION BY WB ---INDETERMINATE. P31 REACTIVE HIV 2 AB NONREACTIVE

My SECOND LAB TEST RESULTS Date( Apr 14 2008) HIV -1 AB CONFIRMATION BY WB-----INDETERMINATE P31 REACTIVE HIV -1 RNA COPIES/ML (V3.0) -----<75 COPIES/ML(<75) HIV 1 RNA LOGCOPIES/ML (V3.0)---<1.88 LOG CPS/ML(<1.88)

Please give me advice on my report .

Response from Dr. Frascino

Hello,

If you obtained these results from an HIV-testing center or a physician's office, you should review these results with them. If you did not, your case points up the problem of getting complex laboratory results from Internet sites or other places that do not have the expertise to explain what the results actually mean!

Your results reveal a preliminary positive (reactive) HIV-antibody test on March 8, which prompted a follow-up, more specific confirmatory test called a Western Blot. The Western Blot results were "indeterminate." That means based on this test they could not determine if you are HIV positive or not. (All tests have limitations.) It's important to note that a positive HIV-antibody test plus an indeterminate Western Blot means your HIV screening result is "indeterminate," not positive.

Follow-up testing on April 14 revealed your Western Blot continued to be indeterminate plus an additional test, an HIV PCR RNA, was performed. The RNA test does not rely on anti-HIV antibodies like the previous two tests you had performed. It detects HIV plasma viral load by assaying for a piece of the viral genetic material (RNA). That test was undetectable ("negative").

Taken together, assuming it's been at least three months since your last potential HIV exposure, your test results indicate you are HIV negative.

You can read more about HIV testing and in particular indeterminate test results in the archives of this forum and on related links.

Dr. Bob



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