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Reassurance with PCR RNA at 6-months

Feb 20, 2008

Hello doc,

Please, I need your opinion about my hiv tests. I had a needlestick event with a potentially contaminated hypodermic syringe 7 months ago.I had symptoms within the window period (sore throat for more than 1 month). My antibody test at three months was negative. I was recommended to be tested again at 6 months, but my clinic decided to do a real time PCR RNA test instead of another antibody test, the result also negative. I've heard some people can give undetectable viral load even without treatments. Do you think these tests are conclusive or would I need a further antibody test?. Thanks in advance Donation is on the way

Response from Dr. Frascino


Although I do not recommend PCR RNA for routine HIV screening, I would say that your negative three-month ELISA coupled with a nondetectable PCR RNA at six months are conclusive. You're HIV negative. The problem with PCR RNA tests is usually false-positive results, not false-negatives.

Thanks for your donation to the Robert James Frascino AIDS Foundation ( It's warmly appreciated.

Be well.

Dr. Bob

Confused by HIV / HBV risks !
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