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Symptoms post PEP
Dec 23, 2007

I had a potential exposure to HIV at the end of September. I started PEP at 12 hrs post exposure. PCR-quantitative was negative, as well as HIV antigen test at 30 days post exposure. On 12/22 I spiked a fever of 101.1F, with no other symptoms. Should I be concerned that I am developing acute HIV infection syndrome?

Response from Dr. Frascino

Hello,

No, I would not immediately jump to that very unlikely conclusion.

I would suggest you follow the recommended guidelines for post-nPEP HIV screening. These guidelines, which can be downloaded at http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5402a1.htm, recommend following a course of nPEP (non-occupational post-exposure prophylaxis) with HIV-antibody testing at three and six months from the time of the HIV exposure. The guidelines do not recommend PCR quantitative tests or HIV-antigen testing.

Good luck.

Dr. Bob



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