|First and last follow-up to a topic seldom covered on your forum
Sep 11, 2007
Dear Dr Bob
Thank you for taking time to answer my questions. I just have a few more concerns. Is it common for hep B antibodies to decrease to undetectable level in a matter of a few years? I had a potential exposure to HIV recently, if I was indeed infected, could the virus break down my hep B antibodies and caused my hep B antibodies level to drop to undetectable level in a few months? Or it is more probable that my vaccine failed right from the start?
| Response from Dr. Frascino
1. No, it is not common for anti-hepatitis B antibodies to fall to undetectable levels following vaccination within a few years.
2. Acquiring HIV infection would not alter anti-hepatitis B antibody levels once established.
3. Yes, the most likely and logical explanation is that your initial vaccination series failed and immunity was never established.
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