thrush and pep
Feb 20, 2006
Dr. Bob, I am police officer and about 4 weeks ago I got a needle stick from an unkn. source patient. I was put on PEP (Retrovir, Epivir & Crixivan) and approx a week and a half into the treament I developed what I believe to be a mild case of thrush. It's been said certian meds can cause thrush and was wondering if the meds I'm taking are on that list. I know this does not have much to do with "Safe Sex and HIV Prevention" but I think your the best thing on this site. I very concerned about this and hope in a couple of months I can do a much needed WOOOHOOO. Thanks so much for all you do.
Response from Dr. Frascino
PEP for a needlestick from an unknown source is rather aggressive therapy unless the source was highly likely to be HIV positive. Did an HIV specialist assess your true level of risk? Also, we seldom recommend Crixivan as part of PEP regimens today, as the dosing requirements are difficult and the mediation can be difficult to tolerate. Personally I feel that anyone who has had an exposure significant enough to warrant PEP should be followed by an HIV specialist to:
1. completely document risk level and decided if PEP is truly warranted;
2. prescribe the most appropriate PEP regimen, if PEP is indicated;
3. monitor PEP therapy and manage any PEP-related toxicities or side effects;
4. arrange and interpret initial and follow-up HIV tests.
Of course, none of this has anything to do with the question you asked, but I decided to add it in for general edification purposes.
Regarding your specific question, it is true some medications can cause thrush, particularly antibiotics and corticosteroids, however, your PEP meds will not.
I'll send my best good-luck karma that you'll be WOO-HOO-ing in two months' time!
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