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Can an ELISA give a false negative if I've been infected for years?
Dec 21, 2005

I read somewhere that an ELISA test can give a false negative if the illness has progressed to the AIDS stage because the body can no longer produce anti-bodies. Is this true?

Response from Dr. Frascino

Hello,

Rare patients have been noted to "serorevert" (become HIV-antibody negative after being HIV-positive) in very late-stage disease. This would give a "false negative" result. However, please note this is very uncommon and does not happen when "the illness has progressed to the AIDS stage," but rather when AIDS becomes very end-stage and the immune system, completely deteriorated. A person would be gravely ill at this stage of disease.

Dr. Bob



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