|Question about results
Nov 10, 2005
Let me start off by saying that I'm low risk. I've had a few screening tests over the past year. I've been donating & that is the reason for the frequent testing. The results have always been negative. My Dr. called me after the last screening & said that my Elisa test came back positive. The lab then did WB. That came back indeterminate. He said there was no hiv band in my blood, but that I would be aggervated because the test was ruled indeterminate because they couldn't get a clear read. He said that I needed to re do the tests so I did. Hiv1 Elisa, WB, PCN came back negative. The Hiv2 Elisa, WB were negative. The lab didn't do Hiv 2 PCN. They were not for sure if that needed to be done. I gave more blood for this test. I haven't heard back. My Dr. has told me that I had a false positive result. I don't understand why the first WB was indeterminate. What would cause an indeterminate? I've spent the last few weeks terrified.
| Response from Dr. Frascino
You are definitively HIV negative. There is no longer any reason to be terrified or even "aggervated."
Indeterminate Western Blot tests are fairly common (from 4 to 20% in some studies!). There are a variety of reasons why an HIV Western Blot may be indeterminate, including:
1. Serologic tests taken during the process or seroconversion
2. Late-stage HIV infection
3. Cross-reacting non-specific antibodies
4. Infection with O strain or HIV-2
5. HIV vaccine recipients (those in clinical trials)
6. Technical errors
7. Clerical errors
That your repeat HIV-1, HIV-2, Western Blot and PCR are all negative is absolutely definitive and conclusive proof that you are HIV negative.
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