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On antivirals built in protection against new strain of virus

Sep 10, 2003

Have asked this before but tono avail. If when a person is exposed to HIV the treatment is a series of antivirals, why would not an HIV positive person, taking antivirals, as in my case, Eprivir, Abacavir and Sustiva, already have some protection against a strain of the virus which is different than the one he already has?

Response from Dr. Frascino


Well he might indeed have some protection from a strain of virus different from the one he already has, but then again he might not! For instance, what if he's exposed to a strain that is resistant to one or more of the meds he's on? See the problem?

You're on Epivir, Abacavir, and Sustiva. There is considerable resistance to Epivir (the M184 mutation) and Sustiva (the K103N mutation) in many communities. If you were re-infected with one of these strains, you risk wiping out your current regimen. We do have documented cases of this happening. Is it worth the risk? Only you can decide.

Dr. Bob

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