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first vs. third

Feb 14, 2002

Any diffference between taking a 1st and 3rd generation Elisa at greater then 6 months?

Response from Mr. Kull

A 1st generation ELISA is likely to be as accurate six months after exposure when compared to 3rd generation ELISA. However, there are some important differences. Early generation assays will detect antibodies to HIV in about 6 to 12 weeks following exposure; newer generation (3rd and 4th) can detect antibodies as early as three to four weeks. Also, newer generation tests are fine tuned to detect antibodies to all known subtypes of HIV. This is not as important for someone whose exposure is limited to the U.S., since subtypes that are commonly found in the U.S. would be detected by 1st generaiton.

Clearly, being antibody tested with newer generation assays is more desirable, and it is unlikely that you would be tested with 1st generation assays in the U.S, unless you use the Home Access testing system.


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