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Response from Dr. Frascino

Hello Surgeon,
The patient jumped out the 4th floor window of the hospital and hit his head on the canopy just as your surgical team was walking by on your way to make rounds? That sounds like it could be an episode of Grey's Anatomy! Hey, maybe you should send them the idea!?!
So surgeon, exactly where were you during medical school and internship when the risk of bloodborne diseases was taught? I find it hard to believe you've made it all the way to your surgical residency without such basic knowledge. I wouldn't allow a first-year medical student onto the wards without a working knowledge of the risks involved in treating patients! Surgeon, it's time you put your scalpel down and do some long overdue remedial work related to occupational exposures to bloodborne pathogens! It might even save your life someday.
The HIV-acquisition risk from the events you describe is nonexistent. Your "ART clinic doc" should have been much more emphatic with his recommendation that post-exposure prophylaxis was not warranted! Regarding your HIV risk, even if splattered with blood, HIV cannot permeate intact skin. Your "chapped (no bleed/ooze) nail-bed edges" would not be an HIV risk. Cutting off the sleeve of your shirt was pure lunacy and the waste of a perfectly good shirt! If the sleeve-stain touched your skin, there would be no HIV risk. (You behaved just like that old surgeon stereotype: cut first, think later!)
Regarding your Combivir (zidovudine/AZT plus lamivudine/3TC), your experience is not uncommon and a good reminder to the readers of this forum that PEP is no picnic. Nausea is common with AZT (zidovudine). AZT can also cause anemia, which in turn can cause fatigue, exercise intolerance and shortness of breath.
My advice would be to discontinue PEP and follow the testing guidelines for an occupational exposure (baseline, six weeks, three months and six months from the date of exposure). If you choose to continue a full 28-day course of PEP, you should check your hemoglobin without delay to see if you have AZT-induced anemia.
Hotdoc, you can read much more about occupational HIV exposures, PEP and ART side effects in the archives. Take a look. And don't forget your refresher course on occupational exposures.
Good luck.
Dr. Bob
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