The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

HIV Drug ResistanceHIV Drug Resistance
Rollover images to visit our other forums!
  • Email Email
  • Glossary Glossary

PEP Questions
Jul 30, 2001

Dear Doctor Little, With your knowledge of acute infection and HIV medications I would like to ask you for information about my situation. I came down with a fever, swollen glands and night sweats 72 hours after insertive vaginal sex with a high risk woman. Based on that, I began PEP(combivir-sustiva) for 30 days. I tested negative for hiv1/2 at 13 weeks post exposure. I plan tofollow up at 6 months and one year. Would you recomend PCR-DNA testing as well because of PEP? Can PEP arrest or delay antibody production? Will I ever know for certain if I am negative, or will having taken PEP cloud the issue. My initial symptoms presented within 3 days and lasted one week. Does that sound like acute HIV? If I were fortunate enough to be under your care how would you advise me to proceed? Thank you for your valuable time. Sincerely, John

Response from Dr. Little

In general, symptoms of acute HIV infection do not begin within 3 days of exposure - the more common presentation is within about 14 days. Regarding your testing, I do not recommend HIV RNA PCR testing in this setting. It sounds like you have already had the appropriate testing and PEP and have the correct plans for follow-up testing. I would not alter your current plans.


  • Email Email
  • Glossary Glossary



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint