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druq on empty stomach
Sep 8, 2007

i frequently take my drugs in the morning on an empty stomach and stay for over 3 hours before eating.is this dangerous.am on troiumune.thanks

Response from Dr. Sherer

No, there is no danger to taking these three drugs - nevirapine (NVP), lamivudine (3TC), and stavudine (D4T) - on an empty stomach. Each of these drugs is well-absorbed without regard to whether or not there is food in the stomach.

It is important to understand that this answer might be different for a different regimen with different drugs. For example, most of the protease inhibitors are better tolerated when taken with food, and food is required for some medications (for example, nelfinavir or efavirenz).

Also in general, I recommend that people take their antiretroviral drugs with food in order to reduce the possible GI side effects. There are some important exceptions, for example DDI-EC once daily requires that it be taken on an empty stomach.

Nonetheless, if you have been doing this without any adverse side effects, there is no reason to change the practice; your trioimmune will be well absorbed.


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