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resistance testing
Oct 4, 2004


when do doctors decide to do a resistance test by infected children?

Response from Dr. Sherer

The indications for resistance testing is essentially the same in adults and children with HIV. The attached website offers recent guidelines for the use of resistance tests that include descriptions of these indications with detailed explanations.

In general, the clearest indications in HIV infected children are: 1) virologic failure in a child on antiretroviral therapy (ART); 2) perinatally acquired HIV infection (both mother and infant); 3) recent HIV infection, i.e. within the past 2 years, or chronic HIV infection in a region in which there is evidence of a >5% prevalence of drug resistance among ART naive patients, in an adolescent.

As this is a complex area, I urge you to discuss this question and the options and materials from the internet with an experienced HIV pediatrician.

Blip as precursor?

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