Aug 24, 2004
How does phenotypic testing work? And is this kind of testing more recommended when you have multiple mutations and have been on lots of regimens?
Response from Dr. Sherer
The appropriate thresholds for the interpretation of phenotype results are still being determined for some drugs, thus the results may be more easily interpreted with some drugs compared to others.
As you suggest, many clinicians obtain a genotype test as their first resistance test due to quicker processing time, lower cost, and earlier changes of genotypes in response to viremia, at a time when relatively few mutations are likely to be found. Similarly, they reserve phenotype tests for more complex patients with multiple past treatment regimens, in whom multiple mutations are likely to be found. In those cases, a phenotype may more accurately reflect how the patient's virus will respond to individual ART drugs.
Time for a PI or not ?
resistant to 3tc
- What Part Of Body Is Affected By Hiv?
- Mood Altering Drug Associated With Hiv
- Peripheral Sensory Neuropathy Symptoms
- Can You Can Become Infected With Hiv From Casual Contact Sharing Eating Utensils Or Drinking Glasses?
- Interferon Side Effects Hep C Treatment
- Over The Counter Drug For Peripheral Neuropathy
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.