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HIV Drug ResistanceHIV Drug Resistance
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Jul 24, 2004

Hi Sorry if this is the 10,000th time you've answered this... I'm on tenofovir, efavirenz and 3TC once a day, started in April. I'm becoming quite relaxed about the exact time of when to take them. it's mean't to be midnight but i'm travelling for 4 months at the moment and finding it hard to be spot on. i kind of think i have an hour each side of 12... is this stupid? thanks for your help Paul

Response from Dr. Sherer

Your best practice is to take the medicines as prescribed, every 12 hours. Most clinicians would agree that there is some 'wriggle room' in this recommendation, and an hour on either side would fit that description. Maybe you and your physician could figure out a schedule that would allow you to err on the lower side more often, and less often on the higher side, just to be as safe as possible.

Huge fluctuations in CD4 levels
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