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HIV Drug ResistanceHIV Drug Resistance
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Mar 16, 2004

my doctor prescribes combivir ONCE a day with sustiva for first month of meds -- no one else agrees that i've asked -- is this a problem and what should i do?

Response from Dr. Sherer

You are correct, there is no once daily dosing of combivir. The correct dose is one pill twice daily. You should inform the doctor that an error has occured, and make your plan with him or her. (A pharamcy error might also explain these events.) I would advise taking the combivir twice daily with the sustiva and quickly obtaining another viral load,CD4 cell count, and a genotype test to look for evidence of an incomplete response and drug resistance.

Finally, if the physician is at fault, an error of this magnitude would be justification for finding another doctor.

can the virus lose resistance?
VL rising, CD4 steady, worried

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