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New study results
Jan 1, 2002

I just read a that at the U.S. National Institutes of Health study of 124 pediatric and adult patients taking protease inhibitors for the first time found that the change in viral load in the first six days of the treatment was able to predict many cases of poor response of the regimen by week 12. Are you putting this information yet into your practice?

Response from Dr. Little

This is difficult to apply in clinical practice since it generally requires at least daily visits to measure viral load. What most providers rely on in clinical practice is the measurement of viral load at week 12/16/20. One would like to see the viral load approaching undetectable or at undetectable by week 12 or 16. Occasionally week 20 or even 24 is used it the starting viral load was very high and/or there was some pre-existing resitance. I am hopeful that drug levels will soon be monitored in clinical practice, which has the potential to improve on our current monitoring tools substantially.

Drop too slow?

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