The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

HIV Drug ResistanceHIV Drug Resistance
Rollover images to visit our other forums!
  • Email Email
  • Glossary Glossary

medication time
Jan 1, 2002

Dear Dr. Little: Thank you for all your help. I am on epivir,ziagen,and sustiva. I would say I am above 95 compliant. The problem is I do not most of the time take the first 2 drugs 12 hrs. apart some times 7-9 hrs. and also sustiva not 24 hrs. sometimes later than normal. As I take sustiva before bed, my bed time is irregular. Is all this a problem and may cause resistance. I would appreciate your opinion.

Thank you once again. John

Response from Dr. Little

Although there is not a great deal of data to refer to in order to advise you regarding the exact timing of your medications, I can tell you that you are unlikely to run into any trouble by moving your Sustiva dose earlier or later by several hours in either direction as long as you take your dose each day. For the other two medications, taken twice daily though, it is a bit more important to try and take the medications as close to the specified time as possible - I generally tell people that plus or minus 2 hours is about the largest window that I would be comfortable with. It sounds like you are very close to this already. If you find that your twice daily meds are more than 14 or less than 10 hours apart, you may want to work on some prompts or reminders that will help you to remember to take them on time. Good luck.

viral load
to stay undetectable!

  • Email Email
  • Glossary Glossary



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint