Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.
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Treatment-Experienced
Feb 28, 2000
Hi, Doctor:
I was Dx'd in 1987 and have survived PCP, MAC and various other 'stuff.' I am very experienced in the treatment arena. My VL has been undetectable only once and has jumped up and down throughout the years. My baseline was 330,000/mL and is currently in the mid-range (64,000). Although my T-4 count is now a whopping 430, the T-4/T-8 ratio has remained constant at .2 over the years.
Recently, after being on a 2-PI/NNRTI/NRTI regimen I stopped the PI's because I just couldn't stand the all the side effects any longer (lipodystrophy syndrome, et al).
[By the way, I read the Body's 'What's New' regularly.]
I feel better (which comes as no surprise!) but am worried about risk. And, at the same time, I'm committed to (somehow) improving my quality of life...I have no 'life.'
[I did the T-20 trials at Hopkins in 1998 and it worked great for me in terms of VL...but it is not available yet.
I couldn't stand IL2.]
Impressions? Where do I go from here? I'm just really exasperated...
Frustrated in D.C.
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Response from Dr. Holodniy
Sorry for not answering this one sooner. Your case is a good one where resistance testing would help me know what I could no longer use, and what I might be able to recycle or turn to.
MH
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