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Involuntary weight loss on efavirenz
Oct 19, 2016

tenofovir disoproxil fumarate, lamivudine & efavirenz. Some times I don't eat well and don't sleep well. I'm not depressed.

Response from Mr. Vergel

Thanks for adding more details to your previous question You are taking what we call Atripla in the US but in 3 separate pills. That regimen is not known to decrease involuntary weight loss. But I am speculating that your appetite may be affected by poor sleep quality, something we know efavirenz can cause.

Talk to your doctor about a potential regimen switch away from efavirenz to see if your appetite and weight increase after your sleep quality improves.

Here are also some options available in the US (I do not know where you live and several of these options may not be available in your country).

How Do I Get My Weight Back When I'm HIV Positive?

Please let me know if you have any further questions. I hope you regain your weight soon.

In health,


lost weight while on ARV
Lipoatrofia miembros inferiores

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