The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Nutrition and ExerciseNutrition and Exercise
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  • Email Email
  • Glossary Glossary

After PEP Questions

Sep 30, 2012

Hello sir,

I had a recent high risk exposure. My condom broke while i had vaginal sex with a csw of unknown status and unprotected oral sex after. This is the first time this happened and i am HIV- to begin with. I took PEP about 5 to 6 hrs later (Combivir and Kaletra) and continued it for 28 days. I took my first dosage at 05.00 to 05.30hrs and 2200 to 2230hrs everyday without fail. I had sinus and cough and develop joint and muscle pains as well as a white hairy tongue somewhere along the course of the medication with the usual associated symptoms associated with taking the drugs such as fatigue and diarrhoea. I got tested at the 4th and 5th(and 5 days) week post exposure and the results were negative (via rapid test), the 5th week being 1 week and 5 days after PEP meds. Currently i still have a cough though not so bad but my joints still hurt quite badly. Also after brushing my tongue it looks better. I'm currently in my 7th plus week post exposure. Questions are,

1) Some ppl told me that PEP doesnt delay sero, others told me otherwise. I'm afraid with the things that i'm feeling that i might be seroconverting. i have no rashes. No fever, just like a moment of feeling heaty for awhile before it goes off. Doesnt last more then a day.right now its just cough and joint pains and a slight whitish tongue.

2) Are my negative test results reliable? Am quite distressed. Should i take another test at week 8 post exposure? That will be 4 weeks off PEP. How conclusive will that be?

Thanks for the time sir. Am really hoping for the best. I've learnt alot from here and am looking forward to your advice.

Response from Mr. Cordova

Hi there:

1) Seroconversion would not be delayed by the course of PEP. If you were to experience ARS, they would most likely also include a fever. Also, while your broken condom was a risk, a one-time incident of penetrative vaginal sex, where you were the insertive partner, and there was some condom use does not sound like a terribly high risk incident to me.

2) By 28 days, most people will show up reactive, or positive on an antibody test. However, you must wait until the 90 day mark for a conclusive result. While your 8 week test is not conclusive, I would feel confident in the negative result. I suggest that you get a final test at the 90 day mark just to be sure.

In health,


Do I have a HIV?
Testosterone lab update question from friend and fan.

  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint