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Nutrition Advice to Lose Weight/Build Muscle
May 10, 2011

I'm 47 years old, currently on Atripla, undetectable with CD4 of 684 and 31%. I'm in good health with no other conditions. I've recently been trying to take some weight off and get myself in better shape by walking, running, and working out. I've been successful with the weight loss by watching what I eat and getting some moderate excercise but I still feel like I'm not progressing in getting more muscle tone. Are there an supplements that might help? Thanks in advance for any advice.

Response from Mr. Vergel

Have your doctor check your thyroid function and total/free testosterone blood levels first to ensure they are within normal ranges.

If your kidneys are ok, you may want to try creatine. But you need to exercise with weights and machines 3-4 times a week for an hour. Follow the suggestions described here: Exercise, the best therapy

This is a summary of a study done in HIV using creatine:

Creatine+ Exercise versus Exercise alone in HIV+ Men:

( from http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2646129 )

Dr Mulligan et al performed a randomized, double blind, placebo-controlled, clinical research center-based, outpatient study in San Francisco. 40 HIVpositive men (20 creatine, 20 placebo) enrolled in a 14-week study. Subjects were randomly assigned to receive creatine monohydrate or placebo for 14 weeks. Treatment began with a loading dose of 20 g/day or an equivalent number of placebo capsules for 5 days, followed by maintenance dosing of 4.8 g/day or placebo. Beginning at week 2 and continuing to week 14, all subjects underwent thrice-weekly supervised resistance exercise while continuing on the assigned study medication (with repeated 6-week cycles of loading and maintenance). The main outcome measurements included muscle strength (one repetition maximum), energetics (31P magnetic resonance spectroscopy), composition and size (magnetic resonance imaging), as well as total body composition (dual-energy X-ray absorptiometry). Thirty-three subjects completed the study (17 creatine, 16 placebo). Strength increased in all 8 muscle groups studied following progressive resistance exercise, but this increase was not augmented by creatine supplementation (average increase 44 vs. 42%, difference 2%, 95% CI −9.5% to 13.9%) in creatine and placebo, respectively). There were no differences between groups in changes in muscle energetics. Thigh muscle cross-sectional area increased following resistance exercise, with no additive effect of creatine. Lean body mass (LBM) increased to a significantly greater extent with creatine.

They saw increases in creatinine in some patients taking creatine, so you need to watch your kidney function. They did not see changes in viral load so hopefully this means that there were no drug-drug interactions with this supplement.



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