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Testosterone Supplementation
Oct 16, 2010

Hello Nelson; Hope you are well and perhaps you can point me in the right direction. I am currently using a RX'd compounded form of testosterone. I rub on a "pea" sized amount of lotion each day and exercise regularly (almost daily), just turned 50 (yikes) and I am on regimen of HIV meds which keeps my viral load undetectable and my numbers good. Recently I noticed a lack of sexual drive and my body just really isn't responding to weight lifting. I would like to add some muscle to my body and was wondering what you would advise; are there other test products that are available that my doctor could RX? Does your body adjust to testosterone supplemants and then level off or drop? Do I need to increase my testosterone or are there other supplements? I just have a lot of questions; do you have archived information on how HIVer's can develop muscle and put on weight especially at my age? For the most part I feel like I'm doing all I can do on my own and I'm a little frustrated. I have a healthy outlook on life and don't feel depressed but notice a slight change in my overall mental health and feel a little down too. Thanks.

Response from Mr. Vergel

First make sure that you are not making any of these mistakes (taken from my book: Testosterone: A Man's Guide, available on Amazon.com or through Paypal. You can read the first 20 pages for free here (210 pages total): Look inside the first 20 pages.

1. Using "street sources" of testosterone: I have met many men whose doctors do not support their use of testosterone, so they buy it on the black market or from some guy at their gyms. This is illegal. Testosterone is classified as a controlled substance under the Anabolic Steroids Control Act of 1990 and has been assigned to Schedule III. It is regulated by the Drug Enforcement Agency (DEA). A doctor can legally prescribe it but it is illegal to use without a prescription. Be aware that the buying or the using of testosterone without a proper prescription may have legal consequences. The use of testosterone and its cousin molecules (anabolic steroids) is illegal in the United States for those without a medical diagnosis that justifies their use (e.g. anemia, wasting, hypogonadism). If after reading this book you still decide to get testosterone in the black market, be beware that you could set up by informants who may alert the DEA of your purchase. Also, importing testosterone even if you have a prescription is not legal. In a nut shell: only use testosterone after a physician gives you a prescription and do not import it from other countries.

The use of "street" testosterone is also dangerous. No one knows what those products may contain. Some so-called testosterone products may simply contain peanut oil, sesame or grape-seed oil. You also run the risk of exposure to contaminants that could cause infection. Not having a doctor follow-up your blood work is a sure way to get in trouble! If you have low testosterone, there are hundreds of doctors who will prescribe testosterone replacement therapy (refer to the Appendix section for directories). If you are using testosterone to increase muscle mass or to improve athletic performance even though you have normal testosterone levels, be smart and research all you can. And please, read the information in this book about how stopping testosterone can cause health problems (if you are using black market testosterone, chances are that your source will eventually run out).

2. Not exploring what testosterone option is best for you: Since there is an assortment of options for testosterone replacement, it's important that you take the time to really find out what's best for you. Several factors are involved in deciding what would be the best testosterone replacement option for you. Among them are cost, insurance coverage, convenience, preference for daily versus weekly use, lack of time to stick to a strict daily schedule, fears of needles, and physician familiarity of the different products. For instance, some health management organizations (HMOs) programs only pay for testosterone injections since they are the cheapest option. However some men have needle-phobia and dislike weekly or bi-weekly injections that may require them to go see their doctors that frequently (some doctors do not teach their patients to self inject at home). Other men are prescribed daily gels even if their busy lives make it difficult to be perfectly compliant to the daily therapy. Some men without insurance or financial means decide not to seek help since they do not know that there are patient assistance programs set up by manufacturers, or the fact that compounding pharmacies can make cheap gels and creams with a doctor prescription (details on this information is available in the Appedix section). Every testosterone option has advantages and disadvantages that may be more suitable for one person over another, so read the following section on treatment options.

3. Not using the right dose: Men who start testosterone need to have their testosterone blood levels rechecked two weeks or one month after they start therapy (depending on the testosterone formulation), right before they administer the corresponding dose for that day or week. This is critical since these results are essential to deciding if the dose is right for you. Total testosterone blood levels under 500 ng/dL that are not improving your sexual desire and energy should be increased to 500 to 1,000 ng/dL by increasing the frequency of injection or the dose. Some doctors fail to retest after they get a patient started on testosterone since they assume most men respond to 200 mg bi-weekly injections or 5 grams per day of gels. The reality is that many men require higher doses to reach total testosterone levels above mid range of normal. Those men tend to stop testosterone early because they perceive no benefits at "average" doses. Incorrect frequency of injections is a common mistake and is actually worse than not getting treatment at all. See the next sections for more details on this.

4. Cycling on and off testosterone: Testosterone replacement is a life-long commitment in most cases. Once you start you should assume that you will stay on it unless you have an unmanageable side effect. Some patients think that "giving the body a break" once every few weeks is a good thing. What they do not know is that during the time that you are taking testosterone, your testicles stop producing it. When you stop replacement therapy you are left with no testosterone in your system for weeks while your HPG hormonal axis normalizes. Depression, weight loss, lack of motivation, and loss of sex drive can appear rapidly and with a vengeance. A few men never have their hormonal axis return to normal after stopping testosterone (especially if they were hypogonadal at baseline). Read more details on this in the section entitled "HPGA dysfunction."

5. Stopping testosterone abruptly due to an unrelated signal: Some of us may be taking medications for other conditions along with testosterone. Sometimes new medications can increase cholesterol and triglycerides and/or liver enzymes (I call these "signals"). Some doctors prematurely blame testosterone instead of the new medications that someone might have started. I have seen people suffer because of this poor judgment of their doctors. Weeks later, they learn that stopping testosterone did not improve any of these problems but by then they feel tired, depressed, and asexual.

6. Not knowing how to manage potential side effects: Luckily, this will not happen to you after you finish reading this book. I know men who stopped testosterone due to swelling in their nipple area, acne, moodiness, perceived lack of benefit, hair loss, or a prostatic specific antigen (PSA) increase that was due to a prostatic infection. Knowing how to manage these side effects is essential to long-term success. If you know what side effects may occur and how to deal with them, you are less likely to prematurely stop therapy. You may just need to readjust the dose, change the delivery method, or take a medication to counteract the potential problem. Only the best physicians, who do not overreact to a side effect, know how to do this.

7. Having a life style that is not "testosterone friendly": If you smoke, drink more than two drinks a day, smoke too much pot, are overweight, do not exercise, do not keep your blood sugar or lipids in control, and do not show up to doctor's appointments, you do not have a testosterone-friendly lifestyle. Studies have shown that these factors may influence your sexual function and long-term health. Excessive alcohol can decrease testosterone. Exercise can increase it if done properly or decrease it if overdone. You can read more about this later in this book.

8. Not reading or staying "networked" with other patients: Being in isolation about information makes you a less effective patient. There are online groups of men who discuss testosterone and other issues (see the Resource section). Sharing your experiences and learning from others are keys to being an empowered and proactive patient. It's the only way to maximize the benefits of any therapy you are using. Many of the practical "tricks" that I have learned have been obtained via this method. The collective wisdom of other people with similar issues is more powerful than just relying on everything your doctor tells, or does not tell you. Besides, most doctors treat educated patients a lot better than those who are timid about sharing and asking questions.

9. Not switching doctors when you have to: Changing doctors can be difficult, especially if you are not a networked patient who reads a lot about your condition. Many people do not have options and have to see a certain doctor in a health management organization (HMO) setting. But most of us have the option of searching for educated doctors who are not condescending and who treat you as an equal. Your doctor should be your partner in your health and not just an unquestioned authority. Although they are saving lives and have spent hundreds of hours in school and practice to do so, they are human beings who are exposed to myths and misconceptions similar to ours I have heard the most irrational things from doctors about testosterone replacement that make me question how unfortunate their patients may be. Be sure to do your homework and find a doctor who supports you in your search for optimum health. See the Resource section for directories of physicians who are trained in testosterone replacement management.

10. Poor compliance: Forgetting when to inject or apply gels is a common complaint. Good time management and reminders are key. Find reminders that work for you. I use Google calendar which can be set up to send me text messages to my phone as reminders. Avoid the yo-yo effect that poor compliance causes! Testosterone replacement is a lifetime and life style commitment that should be explored with care.

If you have not made any of these mistakes and you are still not experiencing the benefits that you want, you can talk to your doctor about using Oxandrin or nandrolone in combination with testosterone. There are several postings in this column from the past that you can search on both products. You can also find more info on Medibolics.com

Nelson



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