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Vitamin D deficiency in HV+ folks on meds

Mar 19, 2010

I was just informed that my vitamin D levels are quite low, under 5. I've been put on 50,000 iu's once a week for 8 weeks, but this has happened before. I always take a 400 iu vit D daily. Was just curious, any correlation between this and meds? My baseline counts in 1995 were, cd4 12, vl 1.5 million, Currently, cd4 at 1317 at 40%, vl, undetectable. So why do I feel like crap and I swear the meds mad me FAT.Im a woman 5 years post hysterectomy oopherectomy. Thanks JB

Response from Mr. Vergel


It seems that we are not metabolizing Vitamin D very well. The hypothesis right now is that probably NNRTIs affect the way the liver processes Vitamin D for use in the body and tenofovir may affect Vitamin D conversion into its active metabolite in the kidneys, but these have not been proven yet.

I am glad you are taking Vitamin D supplementation since it is starting to show up everywhere in research. Vitamin D helps us keep strong bones and may also be linked to lower cancer rates and other health benefits, but data is still very inconclusive and a lot of debate exists right now about Vitamin D function and what normal levels are. I take 2000 units a day to keep my 25-hydroxy vitamin D level above 35 nanograms per deciliter. You can read more on this here:

Vitamin D supplementation and testing

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Testopel Experience

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