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Ask the Experts about Nutrition and Exercise
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High CPK
Oct 3, 2008

I have a high CPK level and I take semcor (cholesterol meds). My doctor is worried because my recent level was 1500, this is after working out hard the week prior. What can i do to lower this level? and is this a serious health risk?

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   Response from Mr. Vergel

CPK is creatine phosphokinase, an enzyme found mainly in the heart, brain, and skeletal muscle.

Do not work out for 5 days and have another test done after that. Working out can increase CPK levels. Your CPK is very high. High CPK can indicate muscle destruction, heart attacks, central nervous sysmtem issues, and others. Statins can cause rhabdomyolysis which can cause dustruction of muscle tissue in few patients.

Some medications can also increase CPK. Among them are amphotericin B, ampicillin, some anesthetics, blood thinners, aspirin, clofibrate, dexamethasone, furosemide, alcohol, and cocaine. CPK increases have also been seen in HIV drug studies, although most of these cases have not been fully explained.

It is very important that you get this under control soon! I am sure you doctor is on top on this right now since it is nothing to be passive about.

Nelson



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