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Viracept-induced diarrhea: Nuisance or Harmful?
Jul 27, 1999
6 months ago my partner started on Fortovase/3TC/D4t, regimen was intensified/adjusted after 3 months, now Viracept/Fortovase/Ziagen/3TC. Working great (thank goodness), VL < 50 from over 500K, CD4 over 200 from under 100. Problem: Significant daily diarrhea from the Viracept. Metamucil is helping some, Immodium some, partner hasn't lost weight, overall he says it's pretty manageable, more of a nuisance than anything else. My question: Any real harm being done? I mean, if he can deal with it, and so far he can, do we need to worry about it? Thanks for your help.
BKS
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Response from Dr. Dieterich
Dear BKS,
You hit the nail on the head. It seems that nelflinavir diarrhea is a nuisance and that's all. Has he tried using pancreatic enzyme supplements like Ultrase mt-20? Some patients have had luck with that plus imodium. The metamucil is a good idea. Douglas T. Dieterich, M.D.
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