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Please Help. PEP and OCD drug interaction.
Apr 18, 2013

I'm taking PEP - Post Exposure Prophylaxis (Truvada, Isentress) but also I have OCD problems so recently I got 4 types of OCD drugs ( Alprazolam, Lexapro, Clomipramine, and Diazepam. Now I am only taking the PEP, I haven't started the OCD drugs. Are there any drug interactions with those drugs?

Response from Dr. Fawcett

Thanks for writing. Be certain to inform your physician about all the drugs you are taking. There typically isn't a problem with these HIV drugs, although combining these various psychotropic drugs can create some side effects such as dizziness and drowsiness, and diazepam with clomipramine can cause a rare but serious condition called serotonin syndrome.

Take care,

David



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